Vrije Universiteit Brussel


Research Page of Sigrid Pieters

Last update: 13/08/2010

General Information

CIVIL STATUS :

  • Born December 19th 1979
  • Belgian

EDUCATION :

  • 2003: Master of Pharmaceutical Sciences, VUB
  • 2008: Master of Industrial Pharmacy, VUB - internship in sterile drug product manufacturing at Pfizer mfg Belgium
  • Since December 2008: PhD student, VUB
  • Since October 2009: Doctoral Fellow of the Research Foundation - Flanders (FWO)

PhD COURSES :

  • June 21-26, 2009: PhD course in Process Analytical Technology, Technical University of Denmark

RESEARCH TOPICS :

  • Analytical Chemistry: chromatography, NIR and Raman spectroscopy
  • Chemometrics: Process Analytical Technology, multivariate calibration, Design of Experiments
  • Pharmaceutical Technology: lyophilization

Publications

  • Pressurized capillary electrochromatography in a screening for possible antioxidant molecules in Mallotus fingerprints: Challenges, potentials and prospects
    S. Pieters, C. Tistaert , G. Alaerts, K. Bodzioch, D. Mangelings, B. Dejaegher, C. Rivière, M. Chau Van, J. Quetin-Leclerq, Y. Vander Heyden
    Talanta - in press

  • Emerging analytical separation techniques with high-throughput potential for pharmaceutical analysis part I: stationary phase and instrumental developments in LC (review)
    Sigrid Pieters, Bieke Dejaegher, Yvan Vander Heyden
    Combinatorial Chemistry and High-Throughput Screening 13 (2010) 510-529

  • Emerging analytical separation techniques with high-throughput potential for pharmaceutical analysis part II: novel chromatographic modes (review)
    Bieke Dejaegher, Sigrid Pieters, Yvan Vander Heyden
    Combinatorial Chemistry and High-Throughput Screening 13 (2010) 530-547

  • Improving the capillary electrophoretic analysis of Poliovirus using a Plackett-Burman design
    Iuliana Oita, Hadewych Halewyck, Sigrid Pieters, Bieke Dejaegher, Bert Thys, Bart Rombaut and Yvan Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 50 (2009) 655-663

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Oral Presentations

  • Chromatographic fingerprints for herbal extracts: set-up and data analysis
    G. Alaerts, M. Dumarey, J. van Erps, S. Pieters, M. Merino-Arévalo, N. Matthijs, B. Dejaegher, J. Smeyers-Verbeke, Y. Vander Heyden
    ISCNP-ISDNP 2010, 7th International Symposium on Chromatography of Natural Products, combined with the 6th International Symposium of the International Society for the Development of Natural Products: The application of analytical methods for the development of natural products - June 14th-17th 2010 - Lublin - Poland

  • Pressurized capillary electrochromatography as an alternative technique to high-performance liquid chromatography for the indication of active compounds in Mallotus species
    Sigrid Pieters, Karolina Bodzioch, Christophe Tistaert, Goedele Alaerts, Bieke Dejaegher, Debby Mangelings and Yvan Vander Heyden
    14 th Forum of Pharmaceutical Sciences, Blankenberge, Belgium, May 14-15th, 2009

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Poster Presentations

  • Process Analytical Technologies: an investment in understanding the pharmaceutical freeze-drying process
    Sigrid Pieters, Thomas De Beer, Dorien Boulpaep, Bieke Dejaegher and Yvan Vander Heyden
    PhD Research Day, Vrije Universiteit Brussel, Brussels, May 28th, 2010

  • Screening for critical process parameters in a pharmaceutical freeze-drying process using a Plackett-Burman design and PAT tools
    Sigrid Pieters, Thomas De Beer, Dorien Boulpaep, Bieke Dejaegher and Yvan Vander Heyden
    26th Annual Symposium on Chemometrics "Knowledge integration & visualization", Utrecht, The Netherlands, May 20th, 2010

  • Pressurized capillary electrochromatography, a useful technique to screen for antioxidant compounds in Mallotus fingerprints?
    Sigrid Pieters, Karolina Bodzioch, Christophe Tistaert, Goedele Alaerts, Bieke Dejaegher, Debby Mangelings and Yvan Vander Heyden
    Recent Developments in Pharmaceutical Analysis 2009, University of Milan, Italy, September 9-12, 2009

  • Screening for antioxidant compounds in Mallotus species using partial least squares regression models built on pressurized capillary electrochromatography fingerprints
    Sigrid Pieters, Karolina Bodzioch, Christophe Tistaert, Goedele Alaerts, Bieke Dejaegher, Debby Mangelings and Yvan Vander Heyden
    PhD course on Process Analytical Technology (PAT), Technical University of Denmark (DTU), June 21-26, 2009

  • Screening for antioxidant compounds in pressurized capillary electrochromatography fingerprints from Mallotus species using partial least squares algorithms
    Sigrid Pieters, Karolina Bodzioch, Christophe Tistaert, Goedele Alaerts, Bieke Dejaegher, Debby Mangelings and Yvan Vander Heyden
    25th Annual Symposium on Chemometrics "Dynamic Chemometrics", Delft, The Netherlands, May 28th, 2009

  • On-line sample preconcentration of Poliovirus particles in a capillary electrophoresis method
    Iuliana Oita, Hadewych Halewyck, Bieke Dejaegher, Sigrid Pieters, Bert Thys, Bart Rombaut and Yvan Vander Heyden
    International Symposium on Capillary Electroseparations Techniques, Catania, Italy, August 2008

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Memberships

  • BGFW
  • Belgian Chemometrics Society (BCS)
  • EUFEPS PAT network

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Coordinates

Sigrid Pieters
Vrije Universiteit Brussel
Faculteit Geneeskunde en Farmacie
Farmaceutisch Instituut
Vakgroep Analytische Scheikunde en Farmaceutische Technologie
Laarbeeklaan 103
B-1090 Brussels Belgium
Tel: (+32) 2 477 45 84
Fax: (+32) 2 477 47 35
Email: Sigrid.Pieters@vub.ac.be


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Laarbeeklaan 103 • 1090 Jette • Tel.: 02/477.47.37 • Fax.: 02/477.47.35 • fabi@vub.ac.be