Vrije Universiteit Brussel


Research Page of Debby Mangelings

Last update: 16/07/2018

General Information

CIVIL STATUS :

  • Born on the 25th of November 1978
  • Belgian
  • Partner of Kristof, mother of Senne

EDUCATION :

  • 29 June 2001: Degree in Pharmacy obtained at the Vrije Universiteit Brussel (VUB) - Belgium
  • 20th of March 2006: Degree of Ph.D. in Pharmaceutical Sciences.
    Title of the thesis: "Evaluation of Capillary Electrochromatography as Chiral Separation Technique - Definition of a Generic Separation Strategy"

ACADEMIC CAREER :

  • October 2001: Ph.D. student in Pharmaceutical Sciences
    Department of Analytical Chemistry and Pharmaceutical Technology (FABI)
    Vrije Universiteit Brussel (VUB) - Belgium

  • October 2006: Postdoctoral Fellow of the Research Foundation - Flanders (FWO)

  • October 2009: Part time assistant professor ("docent")

  • October 2010: Full time assistant professor ("docent")

  • January 2015: Associate professor ("hoofddocent")

RESEARCH TOPICS :

  • Analytical Chemistry:
    Chiral Separations
    Monolithic stationary phases
    Miniaturized separation techniques
    Capillary Electrochromatography
    High Performance Liquid Chromatography
    Capillary Electrophoresis
    Supercritical Fluid Chromatography
  • Chemometrics:
    Experimental design

Prizes


  • February 2004: Applied Physical Chemistry Award for outstanding achievements in the field of chromatography of the Istvan Halasz Foundation, received at HPCE 2004 (Salzburg, Austria)

  • February 2007: Laureate of the National Prize of the Belgian Society of Pharmaceutical Sciences

  • March 2016: LC GC Emerging Leader in Chromatography 2016

Terug naar boven

Publications

    In books

  • 1. "Chiral separations"
    Y. Vander Heyden, D. Mangelings, N. Matthijs and C. Perrin
    Chapter in the "Handbook of Pharmaceutical Analysis by HPLC", S. Ahuja and M. Dong (Eds.), Elsevier, Amsterdam, 2005, pp. 447-498.

  • 2. "Screening approaches for chiral separations"
    D. Mangelings and Y. Vander Heyden
    Chapter in “Advances in Chromatography, volume 46”, E. Grushka, N. Grinberg (Eds.), Taylor and Francis, Florida, 2008, pp.175-211

  • 3. "Recent applications in Capillary Electrochromatography"
    D. Mangelings and Y. Vander Heyden
    Chapter in “Chiral Separations By Capillary Electrophoresis”, A. Van Eeckhaut, Y. Michotte (Eds.), Taylor and Francis, Florida, 2010, pp. 459-500

  • 4. "Application of monolithic chromatography in pharmaceutical analysis"
    D. Mangelings and Y. Vander Heyden
    Chapter in “Monolithic Chromatography and its modern applications”, P. Wang (Ed.), ILM Publications, UK, 2010, pp. 177-213.

  • 5. "Chiral Separations by Capillary Electrophoresis"
    D. Mangelings and Y. Vander Heyden
    Chapter in “Chiral Separation Methods for Pharmaceutical and Biotechnology Products”, S. Ahuja (Ed.), John Wiley and Sons, New Jersey, 2010, pp. 331 - 382.

  • 6. "High-Throughput Screening and Method-Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC and CE"
    H. Ates, D. Mangelings and Y. Vander Heyden
    Chapter in “Chiral Separation Methods for Pharmaceutical and Biotechnology Products”, S. Ahuja (Ed.), John Wiley and Sons, New Jersey, 2010, pp. 383 – 416.

  • 7. "THz biochemical sensing capabilities with high performance SIW based sensor on nL-volume liquids in capillary tubes"
    V. Matvejev, J. Stiens, C. de Tandt, D. Mangelings
    “Terahertz and Mid Infrared Radiation: Detection of Explosives and CBRN (Using Terahertz). NATO Science for Peace and Security Series B: Physics and Biophysics” by Mauro Pereira, Oleksiy Shulika (Eds.), Springer, 2012, pp. 75-80.

  • 8. "Experimental design methodologies in the optimization of chiral CE or CEC separations"
    B. Dejaegher, D. Mangelings and Y. Vander Heyden
    Chapter in G. Scriba (Ed), Chiral Separations, Methods and Protocols, In John M. Walker (Series Ed), Methods in Molecular Biology, Humana Press, 2013, pp. 409-428.

  • 9. "Capillary electrophoresis in chiral separations"
    A. Hendrickx, D. Mangelings and Y. Vander Heyden
    Chapter in “Stereoselective Synthesis of Drugs & Natural Products" by V. Andrushko and N. Andrushko (Ed.), JohnWiley & Sons, 2013, pp. 1549-1570.

  • 10. "Supercritical Fluid Chromatography”
    C. Galea, D. Mangelings, Y. Vander Heyden
    Chapter in Caballero, B., Finglas, P., and Toldrá, F. (Eds.) The Encyclopedia of Food and Health vol. 2, Oxford: Academic Press, 2016, pp. 100-107.

  • 11."Normal-Phase and Polar Organic Solvents Chromatography”
    A.A. Younes, C. Galea, D. Mangelings, Y. Vander Heyden
    Chapter in Analytical Separation Science, First Edition by Jared L. Anderson, Alain Berthod, Verónica Pino Estévez, Apryll M. Stalcup (Ed.), Wiley-VCH Verlag GmbH & Co, 2015, pp 227-244.

  • 12."Separation of stereoisomers”
    C.M. Galea, Y. Vander Heyden, D. Mangelings
    Chapter in Handbooks of Separation Science: Supercritical Fluid Chromatography by C.F. Poole (Ed.), Elsevier, 2017, pp 345-379.

  • 13."Bio-chemical Process Monitoring with Terahertz Sensors”
    Y. Zhang, V. Matvejev, S. Declerck, S. Stroobants, G. Pandey, G. He, D. Mangelings, D. Maes, S. Muyldermans, J. Stiens
    THz for CBRN and Explosives by M. Pereira (Ed), Springer, 2017, pp 29-36.



    In journals

  • 1. "Screening approach for chiral separation of pharmaceuticals Part II. Reversed-phase liquid chromatography"
    C. Perrin, N. Matthijs, D. Mangelings, C. Granier-Loyaux, M. Maftouh, D.L. Massart and Y. Vander Heyden
    Journal of Chromatography A 966 (2002) 119-134.

  • 2. "Enantioseparations of basic and bifunctional pharmaceuticals in capillary electrochromatography using polysaccharide stationary phases"
    D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, D.L. Massart and Y. Vander Heyden Electrophoresis 24 (2003) 2567-2576.

  • 3. "Optimisation of the chlorthalidone chiral separation by capillary electrochromatography using an achiral stationary phase and cyclodextrin in the mobile phase"
    D. Mangelings, C. Perrin, D.L. Massart, M. Maftouh, S. Eeltink, W.Th. Kok, P.J. Schoenmakers and Y. Vander Heyden
    Analytica Chimica Acta 509 (2004) 11-19.

  • 4. "Comparison of the miniaturized techniques capillary electrochromatography and capillary liquid chromatography for the chiral separation of chlorthalidone"
    D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 35 (2004) 789-799.

  • 5. "Compaction of enteric-coated pellets: influence of formulation and process parameters on tablet properties and in vivo evaluation"
    A. Debunne, C. Vervaet, D. Mangelings and J.P. Remon
    European Journal of Pharmaceutical Sciences 22 (2004) 305-314.

  • 6. "Enantioseparations by capillary electrochromatography: differences exhibited by normal- and reversed-phase versions of polysaccharide stationary phases "
    D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden
    Electrophoresis 25 (2004) 2808-2816.

  • 7. "Chemometric modelling of the catalytic hydrogenation of bicarbonate to formate in aqueous media"
    J. Elek, D. Mangelings, F. Joó and Y. Vander Heyden
    Reaction Kinetics and Catalysis Letters 83 (2004) 321-328.

  • 8. "Development and validation of an HPLC method with post-column derivatisation to assay N-acetylcysteïne in plasma"
    Y. Vander Heyden, D. Mangelings, J. Van Brempt and H. Spapen
    Acta Chromatographica 14 (2004) 149-164.

  • 9. "Separation strategy for acidic chiral pharmaceuticals with capillary electrochromatography on polysaccharide stationary phases"
    D. Mangelings, I. Tanret, N. Matthijs, M. Maftouh, D.L. Massart and Y. Vander Heyden
    Electrophoresis 26 (2005) 818-832.

  • 10. "Enantioselective capillary electrophoretic separation of tryptophane- and tyrosine-methylesters in a dual system with a tetra-oxadiaza-crown ether derivative and a cyclodextrin"
    J. Elek, D. Mangelings, T. Iványi, I. Lázár and Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 38 (2005) 601-608.

  • 11. "Strategy for the chiral separation of non-acidic pharmaceuticals using capillary electrochromatography"
    D. Mangelings, J. Discry, M. Maftouh, D.L. Massart and Y. Vander Heyden
    Electrophoresis 26 (2005) 3930-3941.

  • 12. "Capillary electrochromatographic chiral separations with potential for pharmaceutical analysis" (review article)
    D. Mangelings, M. Maftouh and Y. Vander Heyden
    Journal of Separation Science 28 (2005) 691-709.

  • 13. "Generic capillary electrochromatographic screening and optimization strategies for chiral method development"
    D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden
    LC-GC Europe 19 (2006) 40-47.

  • 14. "Newly synthetized tetra-oxadiaza-crown ether derivatives versus commercialized crown-ethers in the separation of positional isomers with capillary electrophoresis"
    P. Forlay-Frick, D. Mangelings, T. Iványi, I. Lázár, K. Héberger and Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 41 (2006) 1164-1170.

  • 15. "Interlaboratory study of a NACE method for the determination of R-timolol content in S-timolol maleate: Assessment of uncertainty"
    R.D. Marini, C. Groom, F.R. Doucet, J. Hawari, Y. Bitar, U. Holzgrabe, R. Gotti, J. Schappler, S. Rudaz, R. Mol, G.W. Somsen, G.J. De Jong, P.T.T. Ha, J. Zhang, A. Van Schepdael, J. Hoogmartens, W. Briône, A. Ceccato, B. Boulanger, D. Mangelings, Y. Vander Heyden, W. Van Ael, I. Jimidar, M. Pedrini, A.-C. Servais, M. Fillet, J. Crommen, E. Rozet, Ph. Hubert
    Electrophoresis 27 (2006) 2386-2399.

  • 16. "The future of high pressure liquid chromatography: Do we need porosity or do we need pressure?"
    G. Desmet, D. Cabooter, P. Gzil, H. Verelst, D. Mangelings, Y. Vander Heyden, D. Clicq
    Journal of Chromatography A 1130 (2006) 158-166.

  • 17. "Enantiomeric impurity determination of levetiracetam using capillary electrochromatography"
    D. Mangelings, J. Saevels, Y. Vander Heyden
    Journal of Separation Science 29 (2006) 2827-2836.

  • 18. "Control of electroosmotic flow by a cation additive to enhance the separation of amino acids by micellar electrokinetic chromatography"
    Q. Qu, X. Tang, D. Mangelings, C. Wang, G. Yang, X. Hu, C. Yan
    Journal of Chromatography B 853 (2007) 31-37.

  • 19. "High-throughput screening and optimization approaches for chiral compounds by means of microfluidic devices" (review article)
    D. Mangelings and Y. Vander Heyden
    Combinatorial Chemistry & High Throughput Screening 10 (2007) 317-325.

  • 20. "Pressurized capillary electrochromatographic assay of trimethoprim impurities using 1 µm particle-based columns"
    Q. Qu, D. Mangelings, F. Shen, X. Hu, C. Yan, Y. Zhang, Y. Vander Heyden
    Journal of Chromatography A 1169 (2007) 228-234.

  • 21. "Evaluation of polymeric methacrylate-based monoliths in capillary electrochromatography: potential for pharmaceutical applications"
    D. Mangelings, I. Tanret, V. Meert, S. Eeltink, P. Schoenmakers, W. Th. Kok, Y. Vander Heyden
    Journal of Chromatographic Science 45 (2007) 578-586.

  • 22. "Reversed-phase column selection for pharmaceutical and compendial analysis: an overview"
    D. Mangelings Y. Vander Heyden
    Published on www.chromedia.nl: Home --> LC basics --> RPLC, Normal Phase,Chiral Chromatography and more --> Reversed Phase (RPLC)

  • 23. "Chiral separations in sub- and supercritical fluid chromatography" (review article)
    D. Mangelings and Y. Vander Heyden
    Journal of Separation Science 31 (2008) 1252-1273.

  • 24"Method development for HILIC assays" (review article)
    B. Dejaegher, D. Mangelings, Y. Vander Heyden
    Journal of Separation Science 31 (2008) 1438-1448.

  • 25. "Influence of the polymerization-mixture composition for monolithic methacrylate-based columns on the electrochromatographic performance of drug molecules"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 264-277.

  • 26. "Fast Generic Chiral Separation Strategies using Electrophoretic and Liquid Chromatographic Techniques"
    H. Ates, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 48 (2008) 288-294.

  • 27. "Chiral Separations in Polar Organic Solvent Chromatography: Updating a Screening Strategy with New Chlorine-containing Polysaccharide-Based Selectors"
    H. Ates, D. Mangelings, Y. Vander Heyden
    Journal of Chromatography B 875 (2008) 57-64.

  • 28. "Pressure-assisted Capillary Electrochromatography versus Capillary Electrochromatography using methacrylate-based monolithic columns: influence of the polymerization-mixture composition"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    Electrophoresis 29 (2008) 4463-4474.

  • 29. "Monolithic silica xerogel capillary column for separations in capillary LC and pressurized capillary electrochromatography"
    Q.-S. Qu, S. Wang, D. Mangelings, C.-Y. Wang, G.-J. Yang, X.-Y. Hu, C. Yan
    Electrophoresis 30 (2009) 1071-1076.

  • 30. "Detection systems for microfluidic devices with a major focus on pharmaceutical and chiral analysis"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    Current Pharmaceutical Analysis 5 (2009) 101-111.

  • 31. "Monolithic stationary phases in classic and chiral pharmaceutical analysis with CEC and pCEC"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    Journal of Chromatographic Science 47 (2009) 407-417.

  • 32. "Monolithic silica capillary columns with immobilized cellulose tris(3,5-dimethylphenyl-carbamate) for enantiomer separations in capillary electrochromatography"
    C. He, A. Hendrickx, D. Mangelings, J. Smeyers-Verbeke, Y. Vander Heyden
    Electrophoresis 30 (2009) 3796-3803.

  • 33. "Sillica Spheres Coated with C18 Modified Gold Nanoparticles for Capillary Liquid Chromatographic and Pressurized Capillary Electrochromatographic Separations"
    Q. Qu, S. Peng, D. Mangelings, X. Hu, C. Yan
    Electrophoresis 31 (2010) 556-562.

  • 34. "Fingerprint development for Ginkgo biloba extracts by pressurized capillary electrochromatography: comparison of column types"
    J. Wang, D. Mangelings, G. Fan, Y. Wu, Y. Vander Heyden
    Journal of Chromatographic Science 48 (2010) 428-435.

  • 35."Microfluidics in macro-biomolecules analysis: Macro inside in a nano world"
    I. Oita, H. Halewyck, B. Thys, B. Rombaut, Y. Vander Heyden, D. Mangelings
    Analytical and Bioanalytical Chemistry 398 (2010) 239–264.

  • 36."Enantioseparations of pharmaceuticals with chlorinated and non-chlorinated polysaccharide-based stationary phases in capillary electrochromatography"
    A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    Electrophoresis 31 (2010) 3207-3216.

  • 37."Permanent gold nanoparticle coatings on polyelectrolyte multilayers modified capillaries for open-tubular capillary electrochromatography"
    Q. Qu, D. Liu, D. Mangelings, C. Yang, X. Hua
    Journal of Chromatography A 1217 (2010) 6588-6594.

  • 38."Pressurized capillary electrochromatography in a screening for possible antioxidant molecules in Mallotus fingerprints: Challenges, potentials and prospects" S. Pieters, C. Tistaert, G. Alaerts, K. Bodzioch, D. Mangelings, B. Dejaegher, C. Rivière, N. Nguyen Hoai, M. Chau Van, J. Quetin-Leclerq, Y. Vander Heyden
    Talanta 83 (2011) 1188-1197.

  • 39."Facile synthesis and size control of highly monodispersed hybrid silica spheres through a novel nuclei controlling method"
    Q. Qu, P. Xu, D. Mangelings, C. Yang, X. Hu
    Journal of Non-crystalline Solids 357 (2011) 976–980.

  • 40."Chiral Separation in Normal-Phase Liquid Chromatography: Enantioselectivity of recently Commercialized Polysaccharide-Based Selectors Part I. Enantioselectivity under generic screening conditions"
    A. A Younes, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 55 (2011) 414–423.

  • 41."Capillary methods for drug analysis"
    A. Hendrickx, D. Mangelings, Y. Vander Heyden
    Journal of AOAC International 94 (2011) 667-702.

  • 42."Chiral separations in normal phase liquid chromatography: Use of new chlorine-containing polysaccharide selectors. Part II: Optimisation strategy"
    A. A. Younes, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 56 (2011) 521-537.

  • 43."Optimizing the separation of acetylsalicylic acid from some of its impurities in CEC on monolithic capillary columns"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    Journal of Separation Science 34 (2011) 2284-2292.

  • 44."Capillary electrochromatographic testing of monolithic silica columns synthesized according to an experimental design approach"
    X. Wu, D. Mangelings, I. Oita, I. Tanret, C. Yan, Y. Vander Heyden
    Journal of Separation Science 34 (2011) 2305-2313.

  • 45."Enantioselective capillary electrochromatography: recent developments and new trends"
    D. Mangelings, Y. Vander Heyden
    Electrophoresis 32 (2011) 2583–2601.

  • 46."Evaluation of the enantioselectivity of monolithic stationary phases immobilized with different concentrations of cellulose tris(3,5-dimethylphenyl-carbamate), analyzed with different mobile phases in capillary electrochromatography"
    C. Lv, D. Mangelings, Y. Vander Heyden
    Electrophoresis 32 (2011) 2708-2717.

  • 47."Updating a chiral separation strategy for non-acidic drugs with capillary electrochromatography applicable for both chlorinated and non-chlorinated polysaccharide selectors"
    A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    Electrophoresis 32 (2011) 2718-2726.

  • 48."Integrated waveguide structure for highly sensitive THz spectroscopy of nano-liter liquids in capillary tubes"
    V. Matvejev, C. de Tandt, W. Ranson, J. Stiens, R. Vounckx, D. Mangelings
    Progress In Electromagnetics Research 121 (2011) 89-101.

  • 49."Combined use of isopropylamine and trifluoroacetic acid in methanol-containing mobile phases for chiral supercritical fluid chromatography"
    K. De Klerck,D. Mangelings, D. Clicq, F. De Boever, Y. Vander Heyden
    Journal of Chromatography A 1234 (2012) 72-79.

  • 50."Amylose 3,5-dimethylphenylcarbamate immobilized on monolithic silica stationary phases for chiral separations in capillary electrochromatography"
    Y. Liu, Y. Vander Heyden, D. Mangelings
    Electrophoresis 33 (2012) 1613–1623.

  • 51."Supercritical fluid chromatography for the enantioseparation of pharmaceuticals"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 69 (2012) 77-92.

  • 52."Enantioselectivity of polysaccharide-based chiral stationary phases in supercritical fluid chromatography using methanol-containing carbon dioxide mobile phases"
    K. De Klerck, G. Parewyck, D. Mangelings, Y. Vander Heyden
    Journal of Chromatography A, 1269 (2012) 336– 345.

  • 53."Chiral Separations in Reversed-Phase Liquid Chromatography: Evaluation of Several Polysaccharide-Based Chiral Stationary Phases for a Separation Strategy Update"
    A.A. Younes , D. Mangelings, Y. Vander Heyden
    Journal of Chromatography A, 1269 (2012) 154– 167

  • 54."Enantioselectivity of polysaccharide-type chiral selectors in polar organic solvent chromatography: implementation of chlorine-containing selectors in a separation strategy" H. Ates, A.A. Younes, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 74 (2013) 1-13.

  • 55."A Separation Strategy Combining three HPLC Modes and Polysaccharide-Based Chiral Stationary Phases"
    A.A. Younes, H. Ates, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 75 (2013) 74-85.

  • 56."Updating a generic screening approach in sub- or supercritical fluidchromatography for the enantioresolution of pharmaceuticals"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    The Journal of Supercritical Fluids 80 (2013) 50-59.

  • 57."Recent advances in SFC for the analysis of chiral and achiral pharmaceuticals"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    LC-GC Europe 26 (5-suppl) (2013) 24-30.

  • 58."Three versus five µm chlorinated polysaccharide-based packings in chiral capillary electrochromatography: efficiency and precision evaluation"
    A. Hendrickx, K. De Klerck,D. Mangelings, L. Clincke, Y. Vander Heyden
    Biomedical Chromatography 28 (2014) 168–181.

  • 59."Three versus five µm chlorinated polysaccharide-based packings in chiral capillary electrochromatography: performance evaluation"
    A. Hendrickx, K. De Klerck,D. Mangelings, L. Clincke, Y. Vander Heyden
    Biomedical Chromatography 28 (2014) 182–191.

  • 60."Exploratory data analysis as a tool for similarity assessment and clustering of chiral polysaccharide-based systems in supercritical fluid chromatography"
    K. De Klerck, Y. Vander Heyden, D. Mangelings
    Journal of Chromatography A 1326 (2014) 110-124.

  • 61."Chiral separability of boron cluster species studied by screening approaches utilizing polysaccharide-based chiral stationary phases"
    D. Mangelings, Y. Vander Heyden, R. Vespalec
    Biomedical Chromatography 28 (2014) 694-707.

  • 62."Pharmaceutical-enantiomers resolution using immobilized polysaccharide-based chiral stationary phases in supercritical fluid chromatography"
    K. De Klerck, Y. Vander Heyden, D. Mangelings
    Journal of Chromatography A 1328 (2014) 85-97.

  • 63."Precision evaluation of chiral capillary electrophoretic methods in the context of inter-instrumental transfer: Constant current versusconstant voltage application"
    B. De Cock, B. Dejaegher, J. Stiens, D. Mangelings, Y. Vander Heyden
    Journal of Chromatography A 1353 (2014) 140-147.

  • 64."Inter-instrumental method transfer of chiral capillary electrophoretic methods using robustness test information"
    B. De Cock, A. Borsuk, B. Dejaegher, J. Stiens, D. Mangelings, Y. Vander Heyden
    Journal of Chromatography A 1353 (2014) 148-159.

  • 65. “Generic chiral method development in supercritical fluid chromatography and ultra-performance supercritical fluid chromatography”
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    Journal of Chromatography A 1363 (2014) 311-322

  • 66. “A chiral separation strategy for acidic drugs using both chlorinated and non-chlorinated polysaccharide-based selectors in capillary electrochromatography”
    D. Albals, A. Hendrickx, L. Clincke, B. Chankvetadze, Y. Vander Heyden, D. Mangelings
    Electrophoresis 35 (2014) 2807–2818

  • 67. “High Enantioselective Novozym 435-Catalyzed Esterification of (R,S)-Flurbiprofen Monitored with a Chiral Stationary Phase”
    T. Siodmiak, D. Mangelings, Y. Vander Heyden, M. Ziegler-Borowska, M. Marszall
    Applied Biochemistry and Biotechnology 175 (2015) 2769-2785.

  • 68. “Method development for impurity profiling in SFC, the selection of a dissimilar set of stationary phases”
    C. Galea, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 111 (2015) 333-343.

  • 69.“Toward greener analytical techniques for the absolute quantification of peptides in pharmaceutical and biological samples”
    A. Van Eeckhaut, D. Mangelings
    Journal of Pharmaceutical and Biomedical Analysis 113 (2015) 181-188.

  • 70.“Characterization and Classification of Stationary Phases in Liquid Chromatography and Supercritical Fluid Chromatography - A Review"
    C. Galea, D. Mangelings, Y. Vander Heyden
    Analytica Chimica Acta, 886 (2015) 1-15.

  • 71.“Inter-instrumental method transfer of a capillary electrophoretic separation of angiotensin II and five derivatives: Evaluation and update of earlier developed guidelines"
    B. De Cock, A. Van Eeckhaut, J. Stiens, D. Mangelings, Y. Vander Heyden
    Electrophoresis 36 (2015) 2658–2664.

  • 72.“Chiral separations of cathinone and amphetamine derivatives: Comparative study between capillary electrochromatography, supercritical fluid chromatography and three liquid chromatographic modes"
    D. Albals, Y. Vander Heyden, M.G. Schmid, B. Chankvetadze, D. Mangelings
    Journal of Pharmaceutical and Biomedical Analysis 121 (2016) 232-243

  • 73.“Comparison of a triple-quadrupole and a quadrupole time-of-flight mass analyzer to quantify 16 opioids in human plasma"
    J. Viaene, K. Lanckmans, B. Dejaegher, D. Mangelings,Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 127 (2016) 49–59

  • 74.“Is the solvation parameter model or its adaptations adequate to account for ionic interactions when characterizing stationary phases for drug impurity profiling with supercritical fluid chromatography?"
    C. Galea, C. West, D. Mangelings,Y. Vander Heyden
    Analytica Chimica Acta 924 (2016) 9-20

  • 75.“Antioxidant activities of Pistacia atlantica extracts modeled as a function of chromatographic fingerprints in order to identify antioxidant markers"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Microchemical Journal 128 (2016) 208–217

  • 76.“Enantioseparations of pharmaceuticals with capillary electrochromatography: a review"
    S. Declerck, Y. Vander Heyden, D. Mangelings
    Journal of Pharmaceutical and Biomedical Analysis 130 (2016) 81–99.

  • 77.“Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using response surface methodology"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Analytical Methods 8 (2016) 6107-6114

  • 78.“Investigation of the effect of mobile phase composition on selectivity using a solvent-triangle based approach in achiral SFC"
    C. Galea, D. Mangelings, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis 132 (2017) 247-257

  • 79.“Seasonal, gender and regional variations in total phenolic, flavonoid and condensed tannins contents and in antioxidant properties from Pistacia atlantica leaves"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Pharmaceutical Biology 55 (2017) 1185-1194

  • 80. “Kinetic study of niobium and tantalum hexameric forms and their substituted ions by capillary electrophoresis in alkaline medium"
    B. De Cock, N. Delaunay, G. Deblonde, V. Bossi, L. Pasti, D. Mangelings, Y. Vander Heyden
    Talanta 175 (2017) 127–134

  • 81. “Interinstrumental transfer of a fast short-end injection capillary electrophoretic method: application to the separation of Niobium, Tantalum and their substituted ions"
    B. De Cock, J. D. Oliver, N. Delaunay, G. Deblonde, D. Mangelings, Y. Vander Heyden
    Electrophoresis 38 (2017) 2069-2074

  • 82. “A label-free detector for liquid chromatography systems using mm-wave technology: first proof of concept"
    Y. Zhang, S. Declerck, D. Mangelings,G. He, V. Matvejev, Y. Vander Heyden, J. Stiens
    Journal of Chromatography A 151 (2017) 79-88

  • 83. “Investigation of the effect of column temperature and back-pressure in achiral SFC within the context of drug impurity profiling"
    C. Muscat Galea, A. Slosse, D. Mangelings,Y. Vander Heyden
    Journal of Chromatography A 1518 (2017) 78–88

  • 84. “Method development for drug impurity profiling in SFC including optimization by statistical experimental design and chromatogram simulation: Application to a pharmaceutical mixture"
    C. Muscat Galea, D. Didion, D. Clicq, D. Mangelings, Y. Vander Heyden
    Journal of Chromatography A 1526 (2017) 128-136

  • 85. “Identification of some bioactive metabolites in fractionated methanol extract from Ipomoea aquatica (aerial parts) through TLC, HPLC, LC-ESI-QTOF-MS and LC-SPE-NMR fingerprint analyses"
    M. Hefny Gad, N. El-Sawi, S. Younes, E-M. El-Ghadban, E. Tuenter, K. Demeyer, L. Pieters, Y. Vander Heyden, D. Mangelings
    Phytochemical analysis 29 (2018) 5-15

  • 86. “Interinstrumental transfer of a chiral capillary electrophoretic method: the use of robustness test information to overcome differences in detector and data-handling specifications"
    B. De Cock, D. Mangelings,Y. Vander Heyden
    Chromatographia 81 (2018) 335-348

  • 87. “Potentially antidiabetic and antihypertensive compounds identified from Pistacia atlantica leaf extracts by LC-MS fingerprinting"
    Z. Ben Ahmed, K. Demeyer, J. Viaene, D. Mangelings, M. Yousfi, B. Dejaegher, Y. Vander Heyden
    Journal of Pharmaceutical and Biomedical Analysis, accepted

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Oral Presentations

  • 1. "Chiral separations with capillary electrochromatography"
    Meeting with Chiral Technologies, 25 September 2003, VUB-Jette-Belgium

  • 2. "Chiral separations by means of capillary electrochromatography: Progress and future developments"
    Meeting with Sanofi Synthelabo, 22 April 2003, VUB-Jette-Belgium

  • 3. "Screening strategy in capillary electrochromatography for chiral pharmaceuticals using polysaccharide stationary phases"
    D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, D.L. Massart and Y. Vander Heyden 11th Forum of Pharmaceutical Sciences, 8-9 May 2003, Spa-Belgium

  • 4. "Capillary electrochromatography: Differences between normal- and reversed-phase stationary phases and future work"
    Meeting with Sanofi Synthelabo, 16 December 2003, VUB-Jette-Belgium

  • 5. "Chiral screening strategy in capillary electrochromatography for acidic substances" Meeting with Sanofi Synthelabo, 08 July 2004, VUB-Jette-Belgium

  • 6. "Chiral separation strategy in capillary electrochromatography: Finalization"
    Meeting with Sanofi Synthelabo, 25 March 2005, VUB-Jette-Belgium

  • 7. "Generic separation strategies in chiral CEC: where are we and what could be the future?"
    D. Mangelings, M. Maftouh, Y. Vander Heyden
    AFSEP symposium, 7 April 2005, Paris, France

  • 8. "Capillary Electrochromatographic Screening and Optimization Strategies for Chiral Method Development"
    D. Mangelings, M. Maftouh, D.L. Massart, Y. Vander Heyden
    HPLC 2005: 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 26-30 June 2005, Stockholm International Fairs-Stockholm-Sweden

  • 9. "Evaluation of Capillary Electrochromatography as Chiral Separation Technique-Definition of a Chiral Separation Strategy"
    D. Mangelings, M. Maftouh, Y. Vander Heyden
    Drug Analysis 2006, 16-19 May 2006, University of Namur-Namur-Belgium

  • 10. "Evaluation of Capillary Electrochromatography as Chiral Separation Technique-Definition of a Chiral Separation Strategy"
    D. Mangelings, M. Maftouh, Y. Vander Heyden
    The Jubilee XXXth Symposium, 12-14 June 2006, Szczyrk-Poland

  • 11. "Evaluation of Capillary Electrochromatography as Chiral Separation Technique. Definition of a Chiral Separation Strategy"
    D. Mangelings, M. Maftouh, Y. Vander Heyden
    2nd Joint CE User Meeting KVCV – KNCV, 17 November 2006, Grobbendonk, Belgium

  • 12. "Evaluation of Capillary Electrochromatography as Chiral Separation Technique-Definition of a Chiral Separation Strategy"
    D. Mangelings
    Algemene Vergadering van het Belgisch Genootschap voor Farmaceutische Wetenschappen, 22 March 2007, Johnson & Johnson, Beerse-Belgium

  • 13. "Evaluation of methacrylate-ester based monoliths for pharmaceutical analysis using capillary electrochromatographic methods"
    D. Mangelings, I. Tanret, Y. Vander Heyden
    HPLC 2007: 31st International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 17-21 June 2007, International Convention Center-Ghent-Belgium

  • 14. "Definition of Generic Chiral Separation Strategies for Pharmaceutical Compounds using Liquid Chromatographic Techniques"
    D. Mangelings, H. Ates, N. Matthijs, Y. Vander Heyden
    RDPA 2007: 12th International Meeting on Recent Developments in Pharmaceutical Analysis, 23-26 September 2007, Elba, Italy

  • 15. "Separation of Chiral Drug Compounds on New Polysaccharide Based Chiral Stationary Phases in Polar Organic Solvent Chromatography"
    H. Ates, D. Mangelings, Y. Vander Heyden
    13th Forum of Pharmaceutical Sciences, 11-12 October 2007, Spa, Belgium

  • 16. "Methacrylate-based monolithic columns in capillary electrochromatography: improving the separation performance by varying the polymerization-mixture composition"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    13th Forum of Pharmaceutical Sciences, 11-12 October 2007, Spa, Belgium

  • 17. "Definition of a chiral separation strategy in capillary electrochromatography and application to a pharmaceutical formulation"
    D. Mangelings, M. Maftouh, J. Saevels , Y. Vander Heyden
    ISCD 20-20th International Symposium on Chirality, 6-9 July 2008, Geneva, Switzerland

  • 18. "Methacrylate-based monolithic columns in (pressurized) capillary electrochromatography: investigating the polymerization mixture composition"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    CEEPUS International Symposium and Summer School on Bioanalysis, 1-10 June 2008, Nitra, Slovakia

  • 19. "Methacrylate-based monolithic columns in (pressurized) capillary electrochromatography: investigating the polymerization mixture composition"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    ITP 2008: International Symposium on Capillary Electroseparation Techniques, 31 August – 4 September 2008, Catania, Italy.

  • 20. "An overview of chiral selectors and separation mechanisms in HPLC and CE"
    Y. Vander Heyden, D. Mangelings
    Invited lecture at the Symposium "Best practice of chiral separations in pharmaceutical development" at Pittcon2009, 8-13 March 2009, Chicago, Illinois, USA, .

  • 21. "Discovering the miniature world of microfluidics"
    I. Tanret, D. Mangelings, A. Gaspar, Y. Vander Heyden
    14th Forum of Pharmaceutical Sciences, 14-15 May 2009, Blankenberge, Belgium.

  • 22. "Performance comparison of chlorine-containing and non-chlorine containing polysaccharide-based selectors for chiral separations"
    H. Ates, D. Mangelings, Y. Vander Heyden
    14th Forum of Pharmaceutical Sciences, 14-15 May 2009, Blankenberge, Belgium.

  • 23. "Bioassay guided isolation of antiplasmodial constituents from Ormocarpum kirkii"
    L. Dhooghe, S. Maregesi, D. Mangelings, Y. Vander Heyden, L. Maes, P. Cos, S. Apers, A. Vlietinck, L. Pieters
    14th Forum of Pharmaceutical Sciences, 14-15 May 2009, Blankenberge, Belgium.

  • 24. "Pressurized capillary electrochromatography as an alternative technique to high-performance liquid chromatography for the indication of active compounds in mallotus species"
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    14th Forum of Pharmaceutical Sciences, 14-15 May 2009, Blankenberge, Belgium.

  • 25. "Chlorine-Containing Polysaccharide-Based Stationary Phases in Chiral Liquid Chromatography"
    H. Ates, D. Mangelings, J. Smeyers-Verbeke, Y. Vander Heyden
    Dag van het Farmaceutisch Onderzoek, 2 June 2009, Mechelen, Belgium.

  • 26. "Methacrylate-based monolithic columns in CEC: the separation of acetylsalicylic acid from its impurities "
    I. Tanret, D. Mangelings, J. Smeyers-Verbeke, Y. Vander Heyden
    Dag van het Farmaceutisch Onderzoek, 2 June 2009, Mechelen, Belgium.

  • 27. "Combining methacrylate-based monolithic separation potential with microfluidic lab-on-a-chip technology: A novel approach"
    I. Tanret, A.Gáspár, D. Mangelings, Y. Vander Heyden
    5th conference by the Nordic Separation Science Society (NoSSS), 26-29 Augustus 2009, Tallinn, Estonia.

  • 28. "Use of Chlorinated polysaccharide-based chiral stationary phases to update generic separation strategies for capillary electrochromatography"
    A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    The XXXIIIrd Symposium: Chromatographic methods of investigating the organic compounds, 25-27 May 2010, Szczyrk-Poland

  • 29. "Evaluation of methacrylate-based monolithic stationary phases for the analysis of drug molecules in the capillary format"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    The XXXIIIrd Symposium: Chromatographic methods of investigating the organic compounds, 25-27 May 2010, Szczyrk-Poland

  • 30. "Polysaccharide-Type Chiral Selectors: The Impact of Chlorine-Containing Groups on Enantioselectivity in Polar Organic Solvent Chromatography"
    H. Ates, D. Mangelings, Y. Vander Heyden
    ISC-2010, 28th International Symposium on Chromatography, 12-16 September 2010, Valencia, Spain

  • 31. "Polysaccharide-Type Chiral Selectors: The Impact of Chlorine-Containing Groups on Enantioselectivity in Polar Organic Solvent Chromatography"
    H. Ates, D. Mangelings, Y. Vander Heyden
    DA-2010, Drug Analysis 2010, 21-24 September 2010, Antwerp, Belgium

  • 32. "Update of a chiral separation strategy for non-acidic drugs with capillary electrochromatography"
    A. Hendrickx, D. Mangelings, Y. Vander Heyden
    PhD day Research Unlimited, 5 April 2011, VUB-Jette, Brussels, Belgium

  • 33. "A chiral separation strategy for non-acidic drugs with capillary electrochromatography"
    A. Hendrickx, D. Mangelings, Y. Vander Heyden
    15th Forum of Pharmaceutical Sciences, 12-13 May 2011, Spa, Belgium

  • 34. "Updating a screening strategy for chiral separations in supercritical fluid chromatography with new chlorinated polysaccharide-based selectors"
    K. De Klerck, G. Parewyck, D. Mangelings, Y. Vander Heyden
    15th Forum of Pharmaceutical Sciences, 12-13 May 2011, Spa, Belgium

  • 35. "Update of Generic Chiral Separation Strategies for Pharmaceutical Compounds using Chromatographic and Electrophoretic Techniques"
    D. Mangelings, H. Ates, K. De Klerck, A. Hendrickx, A. Younes, Y. Vander Heyden
    The XXXIVth Symposium: Chromatographic methods of investigating the organic compounds, 8-10 June 2011, Szczyrk-Poland

  • 36. "Update of Generic Chiral Separation Strategies for Pharmaceutical Compounds using Chromatographic and Electrophoretic Techniques"
    D. Mangelings, H. Ates, K. De Klerck, A. Hendrickx, A. Younes, Y. Vander Heyden
    ISCD 23: 23rd International Symposium on Chirality (Chirality 2011), 10-13 July 2011, Liverpool, United Kingdom

  • 37. "Test set reductions in the development of chiral separation strategies in polar organic solvent chromatography"
    H. Ates, B. Desmedt, D. Mangelings, Y. Vander Heyden
    ISCD 23: 23rd International Symposium on Chirality (Chirality 2011), 10-13 July 2011, Liverpool, United Kingdom

  • 38. "Update of a chiral separation strategy for non-acidic drugs with capillary electrochromatography using chlorinated and non-chlorinated polysaccharide selectors" A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    ISCD 23: 23rd International Symposium on Chirality (Chirality 2011), 10-13 July 2011, Liverpool, United Kingdom

  • 39.Invited lecture: "Chiral Separation Strategies for Pharmaceutical Compounds using Chromatographic and Electrophoretic Techniques"
    D. Mangelings, H. Ates, K. De Klerck, A. Hendrickx, A. Younes, Y. Vander Heyden
    ITP 2011: 18th International Symposium on Electro- and Liquid phase-separation Techniques, 28-31 August 2011, Tbilisi, Georgia

  • 40. "Separations in Normal Phase Liquid Chromatography: Separation Strategy Update Using Recently Introduced Polysaccharide-based Chiral Stationary Phases"
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    PhD day Research Unlimited, 27 March 2012, VUB-Jette, Brussels, Belgium

  • 41. “Updating a generic chiral screening step on polysaccharide-based selectors in supercritical fluid chromatography”
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    16th Forum of Pharmaceutical Sciences, 7-8 May 2012, Blankenberge, Belgium

  • 42.“Fused-core stationary phases for fingerprint development of Phyllantus and Mallotus species”
    G. Parewyck, C. Tistaert, B. Dejaegher D. Mangelings, Y. Vander Heyden
    16th Forum of Pharmaceutical Sciences, 7-8 May 2012, Blankenberge, Belgium

  • 43.“Chiral separations in Reversed-Phase Liquid Chromatography: Enantioselectivity of several polysaccharide-based selectors”
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    16th Forum of Pharmaceutical Sciences, 7-8 May 2012, Blankenberge, Belgium

  • 44. "Update of a generic chiral screening step on polysaccharide-based chiral stationary phases in supercritical fluid chromatography"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    The XXXVth Symposium: Chromatographic methods of investigating the organic compounds, 30 May - 1 June 2012, Szczyrk-Poland

  • 45. "Separation strategies in HPLC for the enantiomeric separation of pharmaceuticals on polysaccharide-based chiral stationary phases"
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    The XXXVth Symposium: Chromatographic methods of investigating the organic compounds, 30 May - 1 June 2012, Szczyrk-Polen

  • 46."Combining Three HPLC Modes and Polysaccharide-based Chiral Stationary Phases in One Generic Separation Strategy"
    D. Mangelings, A.A. Younes, H. Ates, Y. Vander Heyden
    HPLC 2013: 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 16-20 June 2013, Amsterdam, the Netherlands

  • 47.“Precision optimisation of a chiral capillary electrophoretic method: constant current versus constant voltage”
    B. De Cock, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    17th Forum of Pharmaceutical Sciences, 17-18 October 2013, Spa, Belgium

  • 48.“Updating a chiral separation strategy for acidic drugs in Capillary Electrochromatography using chlorinated and non-chlorinated polysaccharides-based selectors”
    D. Albals, Y. Vander Heyden, D. Mangelings
    17th Forum of Pharmaceutical Sciences, 17-18 October 2013, Spa, Belgium

  • 49."Update of a Chiral Separation Strategy in Capillary Electrochromatography using Chlorinated & Non-Chlorinated Polysaccharide-based Selectors"
    D. Mangelings, D. Albals, A. Hendrickx, Y. Vander Heyden
    13th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-13), 29-31 Januari 2014, Bruges, Belgium

  • 50."Supercritical Fluid Chromatography as a tool for chiral separations"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    Waters Technology Days, 19 June 2014, Antwerp, Belgium

  • 51."Definition of a Generic Chiral Separation Strategy on Polysaccharide-based Chiral Stationary Phases in Supercritical Fluid Chromatography"
    D. Mangelings, K. De Klerck, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 52."Inter-instrumental method transfer of a capillary electrophoretic separation of angiotensin II and derivatives"
    B. De Cock, J. Stiens, A. Van Eeckhaut, D. Mangelings, Y. Vander Heyden
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 53.Invited lecture: "Update of a chiral separation strategy in capillary electrochromatography using chlorinated and non-chlorinated polysaccharide-based selectors"
    D. Mangelings, A. Hendrickx, D. Albals, B. Chankvetadze, Y. Vander Heyden
    The XXXVIIIth Symposium: Chromatographic methods of investigating the organic compounds, 26-29 May 2015, Szczyrk-Poland

  • 54."Characterization and classification of stationary phases in SFC (and HPLC)"
    C. Galea, D. Mangelings, Y. Vander Heyden
    The XXXVIIIth Symposium: Chromatographic methods of investigating the organic compounds, 26-29 May 2015, Szczyrk-Poland

  • 55."Method development for impurity profiling in supercritical fluid chromatography: The selection of a dissimilar set of stationary phases"
    C. Galea, D. Mangelings, Y. Vander Heyden
    The XXXVIIIth Symposium: Chromatographic methods of investigating the organic compounds, 26-29 May 2015, Szczyrk-Poland

  • 56."Characterization of Ipomoea reptans extracts through HPLC and HPTLC fingerprint development, phytochemical profiling and in vitro cytotoxicity and antioxidant activity determination"
    M. Hefny Gad, N. Elsawi, E. Elmewafy, S. Younes, Y. Vander Heyden, K. Demeyer, D. Mangelings
    The XXXVIIIth Symposium: Chromatographic methods of investigating the organic compounds, 26-29 May 2015, Szczyrk-Poland

  • 57."Quantitation of opioids in human plasma by means of UPLC-MS: triple quadrupole (QqQ) versus quadrupole-time of flight (Q-tof) mass analyser"
    J. Viaene, K. Lanckmans, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    18th Forum of Pharmaceutical Sciences, 28-29 May 2015, Blankenberge, Belgium

  • 58."Inter-instrumental method transfer of a capillary electrophoretic separation of angiotensin II and derivatives"
    B. De Cock, A. Van Eeckhaut, J. Stiens, D. Mangelings, Y. Vander Heyden
    18th Forum of Pharmaceutical Sciences, 28-29 May 2015, Blankenberge, Belgium

  • 59."Evaluation of core-shell stationary phases in capillary electrochromatography for their potential to separate chiral pharmaceutical compounds"
    S. Declerck, B. Chankvetadze, Y. Vander Heyden, D. Mangelings
    18th Forum of Pharmaceutical Sciences, 28-29 May 2015, Blankenberge, Belgium

  • 60."Herbal chromatographic fingerprints in the search for new drugs: case study of Pistacia atlantica"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings Y. Vander Heyden
    CAC 2015: XV Chemometrics in Analytical Chemistry, 22-26 June 2015, Changsha-China

  • 61.Invited lecture: "Chiral separations in capillary electrochromatography using chlorinated and non-chlorinated polysaccharide-based selectors"
    D. Mangelings, D. Albals, A. Hendrickx, S. Declerck, B. Chankvetadze, Y. Vander Heyden
    PBA 2015: 26th International Symposium on Pharmaceutical and Biomedical Analysis, 5-8 July 2015, Tbilisi-Georgia

  • 62."Characterization and classification of stationary phases in SFC (and HPLC)"
    C. Galea, D. Mangelings, Y. Vander Heyden
    PBA 2015: 26th International Symposium on Pharmaceutical and Biomedical Analysis, 5-8 July 2015, Tbilisi-Georgia

  • 63. "Applications of Chromatographic Fingerprints in the Context of Quality Control of Traditional Herbal Medicines"
    J. Viaene, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    Dag van de Farmacie, 17 September 2015, APB, Brussels, Belgium

  • 64. "Method Development for Impurity Profiling in Supercritical Fluid Chromatography"
    C. Galea, D. Mangelings, Y. Vander Heyden
    Dag van de Farmacie, 17 September 2015, APB, Brussels, Belgium

  • 65. "Comparison of a triple quadrupole and a quadrupole time-of-flight mass analyzer to quantify 16 opioids in human plasma"
    J. Viaene, K. Lanckmans, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    Annual BSMS Meeting, Belgian Society for Mass Spectrometry, 18th September 2015, Vrije Universiteit Brussel, Brussels, Belgium

  • 66. Award lecture: "Generic Chiral Separation Strategies for Pharmaceutical Compounds using Chromatographic and Electrophoretic Techniques"
    D. Mangelings, H. Ates, K. De Klerck, A. Hendrickx, A. Younes, D. Albals, Y. Vander Heyden
    Pittcon 2016, 6-10 March 2016, Atlanta-Georgia (US)

  • 67. "Development of objective identification tests for herbal medicines using multivariate tools on chromatographic herbal fingerprints"
    J. Viaene, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    VUB PhD Research Day 2016, 27 May 2016, VUB-Etterbeek, Brussels, Belgium

  • 68. "Enantioseparations using immobilized polysaccharide-based chiral stationary phases in supercritical fluid chromatography"
    D. Mangelings, K. De Klerck, Y. Vander Heyden
    The 39th Symposium: Chromatographic methods of investigating the organic compounds, 1-3 June 2016, Szczyrk-Poland

  • 69. "A novel label-free and universal detector for liquid chromatography systems using millimeter-wave technology"
    Y. Zhang, S. Declerck, G. He, V. Matvejev, Y. Vander Heyden, D. Mangelings, J. Stiens
    The 39th Symposium: Chromatographic methods of investigating the organic compounds, 1-3 June 2016, Szczyrk-Poland

  • 70. "Methodology development and validation for impurity profiling in supercritical fluid chromatography"
    C. Galea, D. Mangelings, Y. Vander Heyden
    19th Forum of Pharmaceutical Sciences, 17-18 October 2016, Brussels, Belgium

  • 71. "Coupling columns in SFC and retention prediction under isocratic conditions - the "PRISMA" model application"
    I. Salsinha, C. Galea, D. Mangelings, Y. Vander Heyden
    19th Forum of Pharmaceutical Sciences, 17-18 October 2016, Brussels, Belgium

  • 72.Invited lecture: "Enantioseparations using immobilized polysaccharide-based chiral stationary phases in supercritical fluid chromatography"
    D. Mangelings, K. De Klerck, Y. Vander Heyden
    SFC 2016: 10th International Conference on Packed Column SFC, 5-7 October 2016, Vienna, Austria

  • 73. "Optimization of temperature and back pressure in drug-impurity profiling by SFC: a response surface design approach"
    C. M. Galea, D. Didion, D. Clicq, D. Mangelings, Y. Vander Heyden
    HPLC 2017: 45th Symposium International Symposium on High Performance Liquid Phase Separations and Related Techniques, 18-22 June 2017, Prague, Czech Republic

  • 74. "Comparative classification study of Polygonum cuspidatum and Polygonum multiflorum samples based on their UHPLC-DAD and UHPLC-ESI-QTOF fingerprints"
    J. Viaene, K. Segers, M. Kharbach, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    XIX Euroanalysis 2017, Europe's Analytical Chemistry Meeting, 28 August - 1 September 2017, Stockholm, Sweden

  • 75. "Method transfer of capillary electrophoretic methods, development of guidelines to account for interinstrumental differences"
    B. De Cock, D. Mangelings, Y. Vander Heyden
    XIX Euroanalysis 2017, Europe's Analytical Chemistry Meeting, 28 August - 1 September 2017, Stockholm, Sweden

  • 76.Invited lecture: "Transferability of chiral separations in supercritical fluid chromatography"
    D. Mangelings, S. Declerck, Y. Vander Heyden
    APA 2018: 2nd International Symposium on Advances in Pharmaceutical Analysis, 12-13 July 2018, Lille, France

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Poster Presentations

  • 1. "Chromatographic screening strategies for chiral pharmaceuticals implemented in a Knowledge-Based System (KBS) : RPLC and NPLC"
    N. Matthijs, C. Perrin, D. Mangelings, D.L. Massart, Y. Vander Heyden
    ChemoAC Meeting, 7-8 November 2001, VUB - Jette - Belgium

  • 2. "Enantioseparations of basic compounds using cyclodextrins: Comparison of Capillary Electrophoresis and Capillary Electrochromatography"
    D. Mangelings, C. Perrin, D.L. Massart, Y. Vander Heyden
    Drug Analysis 2002, 22-23 april 2002, Bruges-Belgium
    ChemoAC Meeting, 24-25 April 2002, VUB-Jette-Belgium

  • 3. "Experimental design optimization of the chiral separation of chlorthalidone by Capillary Electrochromatography using an achiral stationary phase and cyclodextrin in the mobile phase"
    D. Mangelings, C. Perrin, Y. Vander Heyden
    ChemoAC Meeting, 21-22 November 2002, VUB-Jette-Belgium

  • 4. "Screening strategy in capillary electrochromatography using polysaccharide stationary phases"
    D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, Y. Vander Heyden
    ChemoAC Meeting, 26 March 2003, VUB-Jette-Belgium

  • 5. "Screening strategy in capillary electrochromatography for chiral pharmaceuticals using polysaccharide stationary phases"
    D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, D.L. Massart, Y. Vander Heyden
    HPLC 2003: 27th Symposium on High Performance Liquid Phase Separations and Related Techniques, 15-19 June 2003, Nice-France

  • 6. "Screening strategy in capillary electrochromatography for chiral pharmaceuticals using polysaccharide stationary phases"
    D. Mangelings, N. Hardies, M. Maftouh, C. Suteu, D.L. Massart, Y. Vander Heyden
    KVCV Symposium, Fifth Belgian CE-users Group Meeting, CE-MS in Pharmaceutical Development and Medical Protein Research, 16 October 2003, Janssen Pharmaceutica, Beerse, Belgium

  • 7. "Investigating differences between normal-phase and reversed-phase chiral stationary phases with capillary electrochromatography"
    D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden
    ChemoAC Meeting, 15-16 January 2004, VUB-Jette-Belgium

  • 8. "Differences between normal-phase and reversed-phase polysaccharide chiral stationary phases in capillary electrochromatographic separations"
    D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden
    HPCE 2004: 17th International Symposium on Microscale Separations and Capillary Electrophoresis, 8-12 February 2004, Salzburg-Austria

  • 9. "Defining a screening approach to evaluate the enantioselectivity of acidic drugs in capillary electrochromatography on polysaccharide stationary phases"
    D. Mangelings, M. Maftouh, D.L. Massart and Y. Vander Heyden
    PBA 2004: 15th International Symposium on Pharmaceutical and Biomedical Analysis, 2-6 May 2004, Florence-Italy

  • 10. "Screening approach in capillary electrochromatography for the enantioseparation of acidic pharmaceuticals on polysaccharide stationary phases"
    D. Mangelings, I. Tanret, M. Maftouh, D.L. Massart and Y. Vander Heyden
    ChemoAC Meeting, 10-11 June 2004, VUB-Jette-Belgium

  • 11. "Screening approach in capillary electrochromatography to evaluate the enantioselectivity of acidic drugs on polysaccharide stationary phases"
    D. Mangelings, N. Matthijs, M. Maftouh, D.L. Massart and Y. Vander Heyden
    ISCD-16: 16th International Symposium on Chirality, 11-14 July 2004, New York-USA

  • 12. "Development of a screening strategy in capillary electrochromatography to evaluate the enantioselectivity of acidic drugs on polysaccharide stationary phases"
    D. Mangelings, Y. Vander Heyden, I. Tanret, M. Maftouh and D.L. Massart
    ISC-04: 25th International Symposium on Chromatography, 4-8 October 2004, Paris-France

  • 13. "Application of a chiral separation strategy in capillary electrochromatography for basic, bifunctional and neutral compounds"
    D. Mangelings, J. Discry and M. Maftouh
    ChemoAC Meeting, 9-10 December 2004, VUB-Jette-Belgium

  • 14. "Polar organic mode-based chromatographic chiral screening strategy on polysaccharide columns"
    Y. Vander Heyden, N. Matthijs, D. Mangelings, M. Maftouh, D.L. Massart
    29th symposium ‘Chromatographic methods of investigating the organic compounds’, 8-10 June 2005, Katowice-Szczyrk, Poland

  • 15. "Screening and Optimization Strategies in Chiral Method Development by means of Capillary Electrochromatography and Future Perspectives"
    D. Mangelings, M. Maftouh
    ChemoAC Meeting, 16-17 June 2005, VUB-Jette-Belgium

  • 16. "Polar organic mode-based chromatographic chiral screening strategy on polysaccharide columns"
    Y. Vander Heyden, N. Matthijs, D. Mangelings, M. Maftouh, D.L. Massart
    HPLC 2005: 29th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 26-30 June 2005, Stockholm, Sweden

  • 17. "Separation of chiral drug compounds on new polysaccharide-based stationary phases"
    H. Ates, D. Mangelings, Y. Vander Heyden
    The jubilee XXXIth Symposium chromatographic methods of investigating the organic compounds, 4-6 June 2007, Szczyrk-Poland

  • 18. "Influence of the polymerization mixture composition on the separation performance of methacrylate-ester-based monolithic columns in capillary electrochromatography"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    The jubilee XXXIth Symposium chromatographic methods of investigating the organic compounds, 4-6 June 2007, Szczyrk-Poland

  • 19. "Separation of chiral drug compounds on new polysaccharide-based stationary phases"
    H. Ates, D. Mangelings, Y. Vander Heyden
    HPLC 2007: 31st International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 17-21 June 2007, International Convention Center-Ghent-Belgium

  • 20. "Influence of the polymerization mixture composition on the chromatographic performance of methacrylate-ester-based monolithic columns in capillary electrochromatography "
    I. Tanret, D. Mangelings, Y. Vander Heyden
    HPLC 2007: 31st International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 17-21 June 2007, International Convention Center-Ghent-Belgium

  • 21. "Evaluation of Methacrylate-ester Based Monoliths for Pharmaceutical Analysis Using Capillary Electrochromatographic Methods"
    D. Mangelings, I. Tanret, Y. Vander Heyden
    RDPA 2007: 12th International Meeting on Recent Developments in Pharmaceutical Analysis, 23-26 September 2007, Elba, Italy

  • 22. "(Bio)-Farmaceutische analyse, geïntegreerd practicum"
    D. Mangelings, S. Sarre, K. De Paepe, A. Foriers, Y. Vander Heyden
    Nederlands-Vlaamse Farmacie Onderwijsdag, 25 May 2009, Universiteit Utrecht, Netherlands

  • 23. "Updating and evaluating screening strategies for chiral drug substances using new chlorinated polysaccharide-based stationary phases by means of polar organic solvent chromatography"
    H. Ates, D. Mangelings, Y. Vander Heyden
    ISCD 20: 20th International Symposium on Chirality, 6-9 July 2008, Geneva, Switzerland

  • 24. "Screening for antioxidant compounds in pressurized capillary electrochromatography fingerprints from Mallotus species using partial least squares algorithms"
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    25th Symposium on Chemometrics, 28 May 2009, Delft, Netherlands

  • 25. "New Chlorine-Containing Selectors for High-Throughput Screening of Chiral Drug Compounds Tested in Polar Organic Solvent Chromatography "
    H. Ates,D. Mangelings, J. Smeyers-Verbeke, Y. Vander Heyden
    34th International Symposium on High-Performance Liquid Phase Separations and Related Techniques, 28 June – 2 July 2009, Dresden, Germany

  • 26. "Methacrylate-based monolithic columns in CEC: The separation of acetylsalicylic acid from its impurities"
    I. Tanret, D. Mangelings, Y. Vander Heyden
    5th conference by the Nordic Separation Science Society (NoSSS), 26-29 Augustus 2009, Tallinn, Estland

  • 27. "Evaluation of new types of chiral stationary phases tested in capillary electrochromatography"
    A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    RDPA 2009: 13th international meeting on Recent Developments in Pharmaceutical Analysis, 9-12 September 2009, Milan, Italy

  • 28. "Pressurized capillary electrochromatography, a useful technique to screen for antioxidant compounds in mallotus fingerprints?"
    S. Pieters, K. Bodzioch, C. Tistaert, G. Alaerts, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    RDPA 2009: 13th international meeting on Recent Developments in Pharmaceutical Analysis, 9-12 September 2009, Milan, Italy

  • 29. "Chiral Separations in Normal Phase Liquid Chromatography: Enantioselectivity of Recently Commercialized Polysaccharide-Based Chiral Selectors Part I: Enantioselectivity at Screening Conditions”"
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    PhD Research Day – 28 May 2010 - VUB - Brussels – Belgium

  • 30. "Comparative enantioseparations of pharmaceuticals in capillary electrochromatography on polysaccharide-based chiral stationary phases containing selectors with or without chlorinated derivatives"
    A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    ISC-2010, 28th International Symposium on Chromatography, 12-16 September 2010, Valencia, Spain

  • 31. "Evaluation of methacrylate-based monolithic stationary phases for the analysis of drug molecules in capillary format"
    D. Mangelings, I. Tanret, Y. Vander Heyden
    DA-2010, Drug Analysis 2010, 21-24 september 2010, Antwerp, Belgium

  • 32. "Comparative enantioseparations of pharmaceuticals in capillary electrochromatography on polysaccharide-based chiral stationary phases containing selectors with or without chlorinated derivatives"
    A. Hendrickx, D. Mangelings, B. Chankvetadze, Y. Vander Heyden
    DA-2010, Drug Analysis 2010, 21-24 september 2010, Antwerp, Belgium

  • 33. "Chiral Separations in Normal Phase Liquid Chromatography: Enantioselectivity of Recently Commercialized Polysaccharide-Based Chiral Selectors Part I: Enantioselectivity at screening conditions"
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    DA-2010, Drug Analysis 2010, 21-24 september 2010, Antwerp, Belgium

  • 34. "Updating a screening strategy for chiral separations in supercritical fluid chromatography with new chlorinated polysaccharide-based selectors"
    K. De Klerck, G. Parewyck, D. Mangelings, Y. Vander Heyden
    PhD day Research Unlimited, 5 April 2011, VUB-Jette, Brussels, Belgium

  • 35. "Chiral Separations in Normal Phase Liquid Chromatography: Enantioselectivity of Recently Commercialized Polysaccharide-Based Chiral Selectors Part II: Enantioselectivity at Optimization Conditions"
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    PhD day Research Unlimited, 5 April 2011, VUB-Jette, Brussels, Belgium

  • 36. "Updating a screening strategy for chiral separations in supercritical fluid chromatography with new chlorinated polysaccharide-based selectors"
    K. De Klerck, G. Parewyck, D. Mangelings, Y. Vander Heyden
    The XXXIVth Symposium: Chromatographic methods of investigating the organic compounds, 8-10 June 2011, Szczyrk-Poland

  • 37. "Chiral Separations in Normal Phase Liquid Chromatography: Enantioselectivity of Recently Commercialized Polysaccharide-Based Chiral Selectors Part II: Enantioselectivity at Optimization Conditions"
    A.A. Younes, D. Mangelings, Y. Vander Heyden
    The XXXIVth Symposium: Chromatographic methods of investigating the organic compounds, 8-10 June 2011, Szczyrk-Poland

  • 38. "Updating a generic chiral screening step in supercritical fluid chromatography with new mobile phases and chlorinated polysaccharide-based selectors"
    K. De Klerck, G. Parewyck, D. Mangelings, Y. Vander Heyden
    ISCD 23: 23rd International Symposium on Chirality (Chirality 2011), 10-13 July 2011, Liverpool, United Kingdom

  • 39. "THz Excess Absorption by nL-volume water-alcohol mixtures: model and experimental verification"
    V. Matvejev, C. De Tandt, W. Ranson, D. Mangelings, M. Zizi, J. Stiens
    International Forum on Terahertz Spectroscopy and Imaging, 7-8 March 2012, Kaiserslautern, Germany

  • 40. "Fused-core stationary phases for fingerprint development of Phyllanthus and Mallotus species"
    G. Parewyck, C. Tistaert, B. Dejaegher, D. Mangelings, Yvan Vander Heyden
    PhD day Research Unlimited, 27 March 2012, VUB-Jette, Brussels, Belgium

  • 41. "Updating a generic chiral screening step in supercritical fluid chromatography with new chlorinated polysaccharide-based selectors"
    K. De Klerck, G. Parewyck, D. Mangelings, Y. Vander Heyden
    PhD day Research Unlimited, 27 March 2012, VUB-Jette, Brussels, Belgium

  • 42. "Determination of the critical factors in chiral supercritical fluid chromatography by use of a Plackett-Burman design"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    The XXXVth Symposium: Chromatographic methods of investigating the organic compounds, 30 May - 1 June 2012, Szczyrk-Poland

  • 43. "Fused-core stationary phases for fingerprint development of Phyllantus and Mallotus species"
    G. Parewyck, C. Tistaert, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    The XXXVth Symposium: Chromatographic methods of investigating the organic compounds, 30 May - 1 June 2012, Szczyrk-Poland

  • 44. "Screening the enantioselectivity of polysaccharide-based chiral stationary phases in supercritical fluid chromatography"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    The XXXVIIIth International Symposium on High Performance Liquid Phase Separations and Related Techniques, 16-21 June 2012, Anaheim Marriott, Anaheim, California, USA

  • 45. "Chiral separations in reversed-phase liquid chromatography: enantioselectivity of several polysaccharide-based selectors Part II: separation optimization"
    A.A. Younes, K. De Klerck, D. Mangelings, Y. Vander Heyden
    The XXXVIIIth International Symposium on High Performance Liquid Phase Separations and Related Techniques, 16-21 June 2012, Anaheim Marriott, Anaheim, California, USA

  • 46. "Chlorinated and non-chlorinated polysaccharide-based chiral stationary phases in capillary electrochromatography"
    A. Hendrickx, D. Mangelings, Y. Vander Heyden
    The XXXVIIIth International Symposium on High Performance Liquid Phase Separations and Related Techniques, 16-21 June 2012, Anaheim Marriott, Anaheim, California, USA

  • 47. "Chiral separations in in supercritical fluid chromatography: update of a generic screening step"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    ISC 2012: 29th International Symposium on Chromatography, 9-13 September 2012, Torun, Poland

  • 48. "Fused-core stationary phases for fingerprint development of Phyllanthus and Mallotus species"
    G. Parewyck, J. Viaene, D. Mangelings, Y. Vander Heyden
    ISC 2012: 29th International Symposium on Chromatography, 9-13 September 2012, Torun, Poland

  • 49. "Waveguide-capillary tube integration schemes for the characterization of nano-liter liquids at millimeter wave frequencies with record sensitivities"
    J. Stiens, V. Matvejev, W. De Raedt, D. Mangelings
    IEEE Topical Conference on Bio-medical Wireless Technologies, Networks, and Sensing Systems, 20-23 January 2013, Austin, TX, USA

  • 50. "Transfer of a chiral CE method using precision and robustness testing data"
    B. De Cock, D. Mangelings, Y. Vander Heyden
    Symposium 'Nieuwe ontwikkelingen in de scheidingsmethoden', 19 April 2013, Leiden, The Netherlands

  • 51. "Transfer of a chiral CE method using precision and robustness testing data"
    B. De Cock, D. Mangelings, Y. Vander Heyden
    Nieuwe Ontwikkelingen in scheidingsmethoden, 19 April 2013, Leiden, The Netherlands
    CE Users Meeting, 26 April 2013, Breda, The Netherlands

  • 52. "Updating a chiral separation strategy for acidic drugs in capillary electrochromatography using chlorinated and non-chlorinated polysaccharide-based chiral stationary phases"
    D. Albals, D. Mangelings, Y. Vander Heyden
    CE Users Meeting, 26 April 2013, Breda, The Netherlands

  • 53. "Transfer of a chiral CE method using precision and robustness testing data"
    B. De Cock, D. Mangelings, Y. Vander Heyden
    PhD Day Research Unlimited, 30 May 2013, VUB-Etterbeek, Brussels, Belgium

  • 54. "Precision optimisation of chiral capillary electrophoretic methods: constant current mode"
    B. De Cock, B. Dejaegher, D. Mangelings, Y. Vander Heyden
    HPLC 2013: 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 16-20 June 2013, Amsterdam, the Netherlands.

  • 55. "Implementation of ultraperformance supercritical fluid chromatography (UPSFC) for chiral separations"
    K. De Klerck, D. Mangelings, Y. Vander Heyden
    HPLC 2013: 39th International Symposium on High Performance Liquid Phase Separations and Related Techniques, 16-20 June 2013, Amsterdam, the Netherlands.

  • 56. "Method Development for Drug Impurity Profiling in SFC: The Selection of a Dissimilar set of Stationary Phases"
    C. Galea, Y. Vander Heyden, D. Mangelings
    PhD Day ­ Research Unlimited, 1 April 2014, VUB-Jette, Brussels, Belgium

  • 57. "Comparison of information in HPLC-UV and UPLC-MS fingerprints from Polygonum cuspidatum and Polygonum multiflorum"
    J. Viaene, R. Haex, I. Vincke, B. Casier, D. Mangelings, Y. Vander Heyden
    PhD Day ­ Research Unlimited, 1 April 2014, VUB-Jette, Brussel, Belgium

  • 58. "Precision evaluation of chiral capillary electrophoretic methods in the context of inter-instrumental transfer: constant current versus constant voltage"
    B. De Cock, B. Dejaegher, J. Stiens, D. Mangelings, Y. Vander Heyden
    PhD Day ­ Research Unlimited, 1 April 2014, VUB-Jette, Brussels, Belgium

  • 59. "A chiral separation strategy for acidic drugs in capillary electrochromatography applicable for both chlorinated and non chlorinated stationary phases"
    D. Albals, D. Mangelings, Y. Vander Heyden
    PhD Day ­ Research Unlimited, 1 April 2014, VUB-Jette, Brussels, Belgium

  • 60. "Effects of growing region and maturity stages on lipid yield, fatty acid profile and tocopherols of pistacia atlantica fruit and implications on resulting biodiesel"
    Z. Ben Ahmed, M. Yousfia, J. Viaene, B. Dejaegher, D. Mangelings, K. Demeyer, Y. Vander Heyden
    PhD Day ­ Research Unlimited, 1 April 2014, VUB-Jette, Brussels, Belgium

  • 61. "Phytochemical and Biochemical Studies on Ipomoea reptans"
    M. Hefny Gad, N. Elsawi, E. Elmewafy, S. Younes, K. Demeyer, D. Mangelings, Y. Vander Heyden
    PhD Day ­ Research Unlimited, 1 April 2014, VUB-Jette, Brussels, Belgium

  • 62. "Precision evaluation of chiral capillary electrophoretic methods in the context of inter-instrumental transfer: constant current versus constant voltage application"
    B. De Cock, B. Dejaegher, J. Stiens, D. Mangelings, Y. Vander Heyden
    13th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology (HTC-13), 29-31 January 2014, Bruges, Belgium

  • 63. "Development of a fast enantioselective LC-fluorescence method for amino acids in brain samples by means of fused-core stationary phases: preliminary results"
    D. Mangelings, T. Van Der Stockt, A. Van Eeckhaut
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 64. "Updating a chiral separation strategy for acidic drugs in capillary electrochromatography using chlorinated and non-chlorinated polysaccharide-based selectors"
    D. Albals, D. Mangelings, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 65. "Comparison of information in HPLC-UV and UPLC-MS fingerprints from Polygonum cuspidatum and Polygonum multiflorum"
    J. Viaene, R. Haex, I. Vincke, B. Casier, D. Mangelings, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 66. "Method Development for Drug Impurity Profiling in SFC: The Selection of a Dissimilar set of Stationary Phases"
    C. Galea, Y. Vander Heyden, D. Mangelings
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 67. "Chlorinated and non-chlorinated polysacahride-based chiral stationary phases: Influence of alcohlic mobile phase modifiers on enantioselectivity under NPLC conditions "
    A. Younes, D. Mangelings, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 68. "Inter-instrumental transfer of a chiral CE method guided by precision studies and robustness test data"
    B. De Cock, B. Dejaegher, J. Stiens, D. Mangelings, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 69. "Effects of growing region and maturity stages on lipid yield, fatty acid profile and tocopherols of Pistacia Atlantica fruit and implications on resulting biodiesel"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 70. "Modeling of antioxidant activities of Pistacia atlantica leaves extracts from chromatographic fingerprints and prediction of interesting peaks"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 71. "Phytochemical and biochemical studies on Ipomoea reptans"
    M. Hefny Gad, N. Elsawi, E. A. Elmewafy, S. Younes, Y. Vander Heyden, K. Demeyer, D. Mangelings
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 72. "Development of a fast enantioselective LC-fluorescence method for amino acids in brain samples by means of fused-core stationary phases: preliminary results"
    D. Mangelings, T. Van der Stockt, A. Van Eeckhaut
    Drug Analysis 2014 - 10th International Symposium on Drug Analysis - 25th International Symposium on Pharmaceutical and Biomedical Analysis, 22-25 June 2014, Liège, Belgium

  • 73. "Chromatographic fingerprints to model the antioxidant activity of Pistacia atlantica leaves extracts in order to identify potential antioxidant markers"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Belgian Society for Mass Spectrometry conference day, 7 November 2014, Wavre, Belgium

  • 74. "Chromatographic fingerprints to model the antioxidant activity of Pistacia atlantica leaves extracts in order to identify potential antioxidant markers"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    Chimiometrie XVI, 19-21 January 2015,Geneve, Switserland

  • 75. "Determination of optimal extraction conditions for Pistacia atlantica leaves using response surface methodology"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 76. "Potentially antidiabetic compounds identified from Pistacia atlantica leaf extracts by HPLC-MS fingerprinting"
    Z. Ben Ahmed, M. Yousfi, J. Viaene, B. Dejaegher, K. Demeyer, D. Mangelings, Y. Vander Heyden
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 77. "Fingerprint development of Ipomoea reptans methanolic extract fractions by HPLC and HPTLC: A comparative study"
    M. Hefny Gad, N. Elsawi, S. Younes, E. Elmewafy, K. Demeyer, Y. Vander Heyden, D. Mangelings
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 78. "Evaluation of core-shell stationary phases in capillary electrochromatography for their potential to separate chiral pharmaceutical compounds"
    S. Declerck, B. Chankvetadze, Y. Vander Heyden, D. Mangelings
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 79. "Method Development for Drug Impurity Profiling in SFC: Effect of Modifier"
    C. Galea, D. Mangelings, Y. Vander Heyden
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 80. "Adaptation of the LSER Model to account for Ionic Interactions in SFC"
    C. Galea, C. West, D. Mangelings, Y. Vander Heyden
    4th PhD Day Research Unlimited, 31 March 2015, VUB-Jette, Brussels, Belgium

  • 81. "Evaluation of core-shell stationary phases in capillary electrochromatography for their potential to separate chiral pharmaceutical compounds"
    S. Declerck, B. Chankvetadze, Y. Vander Heyden, D. Mangelings
    HPLC 2015: 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 21-25 June 2015, Geneva, Switserland

  • 82. "Method Development for Drug Impurity Profiling in SFC: Effect of Modifier"
    C. Galea, D. Mangelings, Y. Vander Heyden
    HPLC 2015: 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 21-25 June 2015, Geneva, Switserland

  • 83. "Adaptation of the LSER Model to account for Ionic Interactions in SFC"
    C. Galea, C. West, D. Mangelings, Y. Vander Heyden
    HPLC 2015: 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 21-25 June 2015, Geneva, Switserland

  • 84. "Inter-instrumental method transfer of a CE separation of angiotensin II and derivatives"
    B. De Cock, A. Van Eeckhaut, J. Stiens, D. Mangelings, Y. Vander Heyden
    HPLC 2015: 42nd International Symposium on High Performance Liquid Phase Separations and Related Techniques, 21-25 June 2015, Geneva, Switserland

  • 85. "Potential of core-shell stationary phases to separate chiral pharmaceutical compounds with capillary electrochromatography"
    S. Declerck, B. Chankvetadze, Y. Vander Heyden, D. Mangelings
    VUB PhD Research Day 2016, 27 May 2016, VUB-Etterbeek, Brussels, Belgium

  • 86. "Coupling columns in SFC and retention prediction under isocratic conditions - The 'PRISMA' model application"
    I. Salsinha, C. Galea, D. Mangelings, Y. Vander Heyden
    VUB PhD Research Day 2016, 27 May 2016, VUB-Etterbeek, Brussels, Belgium

  • 87. "Methodology development for profiling of drugs and their impurities or metabolites with supercritical fluid chromatography"
    C. Galea, D. Mangelings, Y. Vander Heyden
    VUB PhD Research Day 2016, 27 May 2016, VUB-Etterbeek, Brussels, Belgium

  • 88."Interinstrumental transfer of a chiral capillary electophoretic method: the use of robustness test information to overcome differences in detector and data-handling specifications"
    B. De Cock, J. Stiens, D. Mangelings, Y. Vander Heyden
    VUB PhD Research Day 2016, 27 May 2016, VUB-Etterbeek, Brussels, Belgium

  • 89."Development of a chiral separation strategy for the analysis of amino acids and small peptides"
    A. Ceuterick, Y. Vander Heyden, D. Mangelings
    VUB PhD Research Day 2016, 27 May 2016, VUB-Etterbeek, Brussels, Belgium

  • 90."Interinstrumental transfer of a chiral capillary electophoretic method: the use of precision studies and robustness test information"
    B. De Cock, N. Delaunay, J. Stiens, D. Mangelings, Y. Vander Heyden
    ISC 2016: 31st International Symposium on Chromatography, 28 August – 01 September 2016, Cork, Ireland

  • 91."Core-shell stationary phases for the separation of chiral pharmaceuticals with capillary electrochromatography"
    S. Declerck, B. Chankvetadze, Y. Vander Heyden, D. Mangelings
    ISC 2016: 31st International Symposium on Chromatography, 28 August – 01 September 2016, Cork, Ireland

  • 92."Coupling columns in SFC under isocratic conditions and retention prediction - 'PRISMA' approach"
    I. Salsinha, C. Galea, D. Mangelings, Y. Vander Heyden
    SFC 2016: 10th International Conference on Packed Column SFC, 5-7 October 2016, Vienna, Austria

  • 93."Characterization of the glycoforms of hCG by chromatographic and electrophoretic separation techniques"
    N. Delaunay, J. Campéri, B. De Cock, A. Combès, D. Mangelings, Y. Vander Heyden, J. Guibourdenche, V. Pichon, T. Fournier
    8th International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules, 1-3 February 2017, Amsterdam, Netherlands

  • 94."Caractérisation de l’hCG par différentes techniques électrophorétiques : CIEF-UV, CZE-UV et CZE-MS"
    J. Campéri, B. De Cock, A. Combès, D. Mangelings, Y. Vander Heyden, J. Guibourdenche, V. Pichon, T. Fournier, N. Delaunay
    12ème Congrès de l'Association Francophone des Sciences Séparatives, 28-30 March 2017, Palais des Expositions de la Porte de Versailles, Paris, France

  • 95."Development of a supercritical fluid chromatographic system to predict the skin permeability of pharmaceutical compounds"
    Y. Grooten, D. Mangelings, Y. Vander Heyden
    PhD-day 2017, 28 March 2017, Jette, Belgium

  • 96."SFC screening on new immobilized chiral stationary phases: ICell 5 & ICell 3"
    S. Declerck, Y. Vander Heyden, D. Mangelings
    PhD-day 2017, 28 March 2017, Jette, Belgium

  • 97."Nanoparticle-Modified Affinity Silica Monoliths for Chiral Separations by Capillary Electrochromatography"
    T. Hong, Y. Ji, D. Mangelings, Y. Vander Heyden
    PhD-day 2017, 28 March 2017, Jette, Belgium

  • 98."Development of a supercritical fluid chromatographic system to predict the skin permeability of pharmaceutical compounds"
    Y. Grooten, D. Mangelings, Y. Vander Heyden
    HPLC 2017: 45th Symposium International Symposium on High Performance Liquid Phase Separations and Related Techniques, 18-22 June 2017, Prague, Czech Republic

  • 99."Transfer of chiral separations in supercritical fluid chromatography"
    S. Declerck, Y. Vander Heyden, D. Mangelings
    XIX Euroanalysis 2017, Europe's Analytical Chemistry Meeting, 28 August - 1 September 2017, Stockholm, Sweden

  • 100."Combined separation strategy for chiral method development of acidic and non-acidic pharmaceutical compounds in capillary electrochromatography (CEC)"
    D. Albals, A. Hendrickx, D. Mangelings, Y. Vander Heyden
    The 20th Congress of the Arab Association of the Faculties of Pharmacy: The 5th International Conference of the Jordanian Faculties of Pharmacy: The 2nd International Conference of the Faculty of Pharmacy, 7-9 November 2017, Amman, Jordan

  • 101."Comparison of Unispray and Electrospray for the ionization of neuropeptides"
    J. Bongaerts, K. Segers, Y. Van Wanseele, M. Van Hulle, L. Van Oudenhove, I. Smolders, D. Mangelings, Y. Vander Heyden, A. Van Eeckhaut
    4th EBF YYS The BioA Brain- Embracing New Ideas; 15-16 March 2018 – Ghent- Belgium
    PhD day 2018; 20 March 2018- Jette-Belgium

  • 102."Cannabis profiling for forensic intelligence improvement using GC/MS, multivariate data analysis and statistical methodology"
    A. Slosse, F. Van Durme, N. Samyn, D. Mangelings, Y. Vander Heyden
    PhD day 2018; 20 March 2018- Jette-Belgium

  • 103."Development of a micellar liquid chromatography method to predict the skin permeability of pharmaceutical compounds"
    Y. Grooten, Q. Marcelis, D. Mangelings, Y. Vander Heyden
    PhD day 2018; 20 March 2018- Jette-Belgium

  • 104."Transfer of chiral separations in supercritical fluid chromatography"
    S. Declerck, Y. Vander Heyden, D. Mangelings
    PhD day 2018; 20 March 2018- Jette-Belgium

  • 105."Comparison of Unispray and Electrospray for the ionization of neuropeptides"
    J. Bongaerts, K. Segers, Y. Van Wanseele, M. Van Hulle, L. Van Oudenhove, I. Smolders, D. Mangelings, Y. Vander Heyden, A. Van Eeckhaut
    BSMS Annual Meeting 2018- 29 March 2018- Liège-Belgium

Terug naar boven

Memberships

  • Belgisch Genootschap voor Farmaceutische Wetenschappen (Belgian Society of Pharmaceutical Sciences) (BGFW)

Terug naar boven

Coordinates

Vrije Universiteit Brussel
Faculteit Geneeskunde en Farmacie
Vakgroep Farmaceutische en Farmacologische Wetenschappen
Department of Analytical Chemistry, Applied Chemometrics and Molecular Modelling
Laarbeeklaan 103
B-1090 Brussels Belgium
Tel: (+32) 2 477 43 29
Fax: (+32) 2 477 47 35
Email: debby.mangelings@vub.ac.be

©1997-2005 • FABI • Vrije Universiteit Brussel • Faculteit Geneeskunde & Farmacie
Laarbeeklaan 103 • 1090 Jette • Tel.: 02/477.47.37 • Fax.: 02/477.47.35 • fabi@vub.ac.be